Opioid Morphine Equivalent Calculator
opioid mme calculator. Get instant, accurate results. Enter values for instant results with step-by-step formulas.
Reviewed by Rahul Singh, Health & Wellness Specialist
Formula
Daily MME = (Dose per administration) × (Doses per day) × (Conversion factor) | Fentanyl patch: mcg/hr × 2.4 | Methadone: nonlinear CDC table
Conversion factors vary by opioid: oxycodone ×1.5, hydromorphone ×4, codeine ×0.15, tramadol ×0.1, morphine ×1, hydrocodone ×1. Methadone and fentanyl use special calculations. The result represents total daily morphine-equivalent exposure.
Worked Examples
Example 1: Oxycodone 10 mg QID
Problem:Oxycodone 10 mg taken 4 times daily.
Solution:Daily dose: 10 × 4 = 40 mg. MME = 40 × 1.5 = 60 MME/day.
Result:60 MME/day — Increased Risk (≥50 MME)
Example 2: Fentanyl Patch 50 mcg/hr
Problem:Transdermal fentanyl 50 mcg/hr patch, changed every 72 hours.
Solution:Daily MME ≈ 50 × 2.4 = 120 MME/day.
Result:120 MME/day — High Risk (≥90 MME)
Frequently Asked Questions
What is MME (Morphine Milligram Equivalent)?
MME standardizes opioid doses to an equivalent amount of oral morphine. It allows clinicians to compare the strength of different opioids and assess total daily opioid exposure regardless of which medications are prescribed. The CDC publishes conversion factors that are widely used in clinical practice and quality measurement.
References
Reviewed by Rahul Singh, Health & Wellness Specialist · Editorial policy